Past Research Programs

Ching-Pin Chang, MD Stanford University	Method for evaluating and improving outcomes in pediatric cardiac catheterization Amount Awarded: 2006 — $99,839
Jeffrey Phillip Jacobs, MD Cardiac Surgical Associates	Congenital heart disease multi-societal project to create a universal encyclopedia for definitions of preoperative risk factors and postoperative complications related to congenital heart surgery and interventions Amount Awarded: 2006 — $50,000
Margaret L. Kirby, PhD Duke University Medical Center	Normal cardiac outflow tract development depends on retinoic acid signaling Amount Awarded: 2006 — $88,073
Brian W. McCrindle, MD Hospital for Sick Children	Late functional status in a cohort of survivors with pulmonary artresia intact ventricular septum from the congenital heart surgeons society study Amount Awarded: 2006 — $86,308
Henry Michael Spotnitz, MD Columbia University	Myocardial protection and support in cyanotic congenital heart disease Amount Awarded: 2006 — $96,938
Pirooz Eghtesady, MD Children's Hospital, Cincinnati	Role of nitric oxide in the increased placental vascular resistance following cardiopulmonary bypass Amount Awarded in 2005 — $36,479 Amount Awarded in 2006 — $36,479
Nancy Ghanayem, MD Medical College of Wisconsin	Neurodevelopmental outcomes and postoperative hemodynamics in children with hypoplastic left heart syndrome Amount Awarded in 2005 — $60,000 Amount Awarded in 2006 — $60,000
Lisa Bergersen, MD Children's Hospital, Boston	Method for evaluating and improving outcomes in pediatric cardiac catheterization Amount Awarded in 2005 — $56,000
Kenneth O. Schowengerdt, MD University of Florida College of Medicine	The role of neutrophil—derived factors in the pathogenesis of cardiac allograft vasculopathy Amount Awarded in 2005 — $70,000
Aarti Hejmadi Bhat, MD Oregon Health Sciences Univ. / University of California at San Francisco	Progression of ventricular mass and morphology and conotruncal volume with gestation: a study of normal and abnormal fetal hearts with three and 4D ultrasound Amount Awarded in 2005 — $60,000 Amount Awarded in 2004 — $60,000
Emmanuele Delot, MD Univ. of California Los Angeles	BMP signaling in DiGeorge syndrome mouse models Amount Awarded in 2005 — $70,000 Amount Awarded in 2004 — $70,000
Marshall Jacobs, MD Congenital Heart Surgeons Society	The Congenital Heart Surgeons Society multi-institutional study: pulmonary ventricle-pulmonary artery conduits in infants and young children Amount Awarded in 2005 — $50,000 Amount Awarded in 2004 — $50,000
Tajinder P. Singh, MD Wayne State University	Myocardial flow reserve and sympathetic reinnervation after arterial switch operation Amount Awarded in 2004 — $36,800 Amount Awarded in 2006 — $36,000
Tara Dixon MD Ross Ungerlieder MD Oregon Health and Science University	Development of the optimal strategy for extracorporeal circulation in infants: can the application of a miniaturized circuit and an asanguineous prime allow modification of perfusion parameters to improve outcomes following cardiopulmonary bypass? Amount Awarded in 2004 — $58,643
Tara B. Karamlou, PhD Oregon Health and Science University	Modifying risk for infant cardiopulmonary bypass: use of a miniaturized circuit and an asanguineous prime to reduce meutrophil-mediated organ dysfunction Amount Awarded in 2004 — $25,000 Amount Awarded in 2003 — $40,000

D. Woodrow Benson, MD Cincinnati Children's Hospital Medical Center	Ebstein anomaly: molecular genetic studies of a canine equivalent Amount Awarded in 2002 — $51,123
Alvin Chin, MD Children's Hospital of Philadelphia	Identification and analysis of zebrafish models of eterotaxy syndrome Amount Awarded in 2001 — $100,000
Lazaros Kochilas, MD University of Pennsylvania	Molecular regulation of neural crest contribution in the developing cardiac outflow tract Amount Awarded in 2001 — $45,000 Amount Awarded in 2000 — $41,400
Diane Hoffman—Kim, PhD Brown Univ. School of Medicine	Tissue engineered pediatric cardiac valve replacement Amount Awarded in 2001 — $88,755 Amount Awarded in 2000 — $93,357 Amount Awarded in 1999 — $92,715
Cynthia Morris, PhD Oregon Health Sciences University	Prevalence of MTHFR mutations in children with conotruncal defects and their mothers Amount Awarded in 2003 — $40,484 Amount Awarded in 2000 — $47,414
Jeffrey Pearl, PhD Children's Hospital Medical Center	The effects of methylprednisolone on the inflammatory response induced by cardiopulmonary bypass during the repair of congenital heart disease Amount Awarded in 2005 — $70,000 Amount Awarded in 2004 — $70,000
Madhu Gupta, PhD The Heart Institute for Children, Hope Children's Hospital	Regulation of myosin gene expression in hypertrophy and in heart development Amount Awarded in 2000 — $24,666 Amount Awarded in 1998 — $32,666
Daniel Rappolee, PhD Northwestern Uniersity . Medical Center	The role of FGF in the development of the first contractile heart muscle Amount Awarded in 2000 — $10,000 Amount Awarded in 1999 — $40,000

David J. Sahn, MD Oregon Health and Science University	In vitro studies of embryonic heart flows & fluid dynamics based on 3D models [TWO YEAR PROJECT] Amount Awarded in 1999 — $75,000 Amount Awarded in 1998 — $75,000
Eliot R. Rosencranz, MD Children's Hospital of Buffalo	Endogenous mechanisms of ischemia tolerance of the developing heart [TWO YEAR PROJECT] Amount Awarded in 1999 — $23,850 Amount Awarded in 1998 — $24,550
Constantine Mavroudis, MD Children's Memorial Hospital, Chicago, IL	A new operation for congenitally corrected transportation, ventricular septal defect and pulmonary stenosis Amount Awarded in 1999 — $85,109
Susan Crawford, MD Children's Memorial Hospital, Chicago, IL	Regulation of angiogenic inhibitors in cardiac remodeling and hypertrophy Amount Awarded in 2001 — $100,000
G. Paul Matherne, MD University of Virginia Health Sciences Center	Molecular regulation of neural crest contribution in the developing cardiac outflow tract Amount Awarded in 1997 — $48,601
Paul J. Chai, MD Duke University Medical Center	Tissue engineered pediatric cardiac valve replacement Amount Awarded in 1997 — $20,735

The Children's Heart Foundation is a not-for-profit organization that funds the most promising research to advance the diagnosis, treatment and prevention of congenital heart defects.

The information in ChildrensHeartFoundation.org is not intended as a substitute for medical professional help or advice but is to be used only as an aid in understanding congenital heart disease.

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